






Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog’s entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.
Is Discontinued By Manufacturer : No
Product Dimensions : 5.75 x 0.75 x 4.5 inches; 1.6 ounces
Manufacturer recommended age : 1 month and up
Item model number : 72220
Department : Flea & Tick
Date First Available : May 30, 2004
Manufacturer : Boehringer Ingelheim Animal Health
ASIN : B0002J1FP8
Best Sellers Rank: #2,721 in Pet Supplies (See Top 100 in Pet Supplies) #13 in Dog Flea Drops
Customer Reviews: 4.4 4.4 out of 5 stars (15,067) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
9 reviews for FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments
Add a review
$39.98
Toy Lee –
This stuff still works great
I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven’t seen any in years! I’m glad I found it on Amazon! Because I can’t afford the other stuff & too! The other stuff I don’t really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she’s not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder’s! So thankful they still make Frontline & it works! Am definitely going to be buying more!
Susan the Grouch –
Still works in my part of the state
Easy to apply if you can make a part in your dog’s hair.I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess.Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away…
Richard Hopkins –
There ain’t no bugs on Skip or Rayne!
Works as it should! No fleas and no ticks! Easy to apply and lasts 90days with no weird smell.
Kindle Customer –
Flea med
Helps but bad year and not lasting for maybe 2weeks at most on the dogs
Krystina J –
Best flea and tick med!
Arrived quickly. Always works so well for fleas and ticks for our 2 German Shepherds (very thick hair). We live on lots of land with woods so they come into contact with fleas/ticks, but when Frontline is used, we don’t have any problems. Love the bigger pack that is offered and at the best price!!Fleas:No fleas on our dogs!Ease of application:Just takes a few seconds to apply!
Amie Kennedy –
Good product
Product works well, I live in Florida, off grid, in the woods. We have lots of sand, and my lab is active and always playing in the forest. I never have problems with ticks or fleas. Nats are still a pain, but I use Avons, Skin So Soft, I spray it on my hands, lightly pass over her eyes, back and tail. I’ve never seen skin or eye irritation from any of my dogs. From the flea control or the Skin so soft. Hope this helps.
Bamby Lockwood –
Worked better than other flea and tick treatments
Worked better than other flea and tick treatments. Lasted longer
5550 –
WASTE OF MONEY DOESN’T WORK!!!!
Since application I have literally pulled off seven ticks. Some attached some crawling to attach. Literally pulled two off within 6 hours of application. The rest have been within the last week. We have Lyme disease here. This was the reason why I got this. If my dog ends up with Lyme disease you’ll end up with a bill!! I want my money back. Don’t listen to their money back. Guarantee you call that number on the back of the box and they just want to find all sorts of loopholes of reasons. Why not to give you your money back. They want ticks to eat on your dog up to 3 months! It doesn’t matter where I purchased it. The facts are the facts. It does not work! seven ticks 3 weeks. Says “kills ticks including those that may transmit Lyme disease” when you talk to the company they say it doesn’t protect against Lyme disease! Fair the definition of what’s wrong with companies finding loopholes to basically screw over their customers.
Zee –
It says there is 6 doses inside but i received only 3 and package was opened!